I like how you varied the subtitles with color and italicization, but do consider proofreading. "A bit" was put as one word again, "at least" was also meshed into one word, at least three words were missing apostrophes, and you wrote 'seem' instead of 'see'.

I appreciate the effort you put into making an opening and ending, but when it's something relatively short (compared to a common anime episode, 20-24 minutes) they don't need to be so long and I think the effort would be out to better use in having more movement in the actual episode. Actually, even in the opening, the characters really don't move much. You're mostly doing static punch shots, like in old anime, but that was a budget-saving technique, not really something to look up to. At least make sure there's a bit more movement in other stuff if you're going for that impactful close-up semi-still shot of a hit or something like that. It feels really slow watching these not very detailed characters standing still when talking and sometimes when fighting. Just look at Clyde's lunge towards the end. He spends a good 2 seconds not moving, at the same distance. Just speed things up. I get that you have yo give people time to read the subtitles, but maybe make the dialogue a little bit more scarce then so the whole thing will move faster. That or, again, make things a bit more animated, less static. Also, so much time was spent on talking and that shoehorned-in infomercial joke which broke the flow that the fight ended up being pretty forgettable and seemed unnaturally short.
Keep it up, this does have potential, I like the characters, but it's still pretty rough.