There has been an absolutely abundance of Game Grumps animations recently, though they never get old - at least in my opinion.
You chose a good audio clip from Game Grumps to animate. However, this would have been a lot better with some simple touch-ups. The execution of this was done well, though the animation could be better.
A lot of the changes in facial expressions appear choppy, but this could easily be fixed with an inbetween or two. They make the change look much more natural and a lot better than just an abrupt change between drawings.
The character designs could use some work. They look a bit sloppy, but if they were cleaned up, this would be very good.
The way you chose to interpret that part was absolutely hilarious. Unfortunately, the abrupt ending when it ends on that frame lets this cartoon down.
Keep up the good work, and good luck on your future endeavors!