While it IS extremely tempting to retreat into your mind and block out reality (believe me, I know), you can't, because you can't close yourself off from the entire world and live in a lie your mind creates and shapes, because the world is a necessary componet to living. And you especially cannot close yourself off from the people that care or don't care about you, because it's selfish and cowardice, because people may need you in their lives... whether you believe it or not.
Great animation, great story, and great theme!