Milkshake=pwnage
That was great. Normally, blood and sprites have not been good to me, but this was different somehow. Maybe it was because it was Mario. I think the best thing I can do for you is tell you why you were able to get away with a lot of blood and the sprites.
Blood: The characters kept coming back. For some reason I didn't care if the sprites got killed. It was always in good humor, too. Such as Toad in the castle cleaning scene or Bowser in the last scene. The only scene that abused this was the "Aliens?" scene. That one seemed totally pointless and largely seemed to bring down the package.
Sprites: You were making fun of one particular game, so it seemed fair. It felt like you were watching Super Mario World, but it wouldn't have if you had hand-drawn the images. Good choice. I also liked your use of sprites from other games where appropriate (Lion King and Frogger) and the use of the Princess Peach's Castle sprite set. I love that one. Oh, dag. I'm such a nerd... I'm talking about one specific set of sprites of all of the sprites on the internet...
My only suggestion for you is to be leniant with the blood and death next time. It'll get old fast. The castle cleaner scene was my absolute favorite, and I would love to see more like that. Sound played a big roll in why I loved your Flash. You have very nice comedic timing. The only reason you didn't get a ten was the "Aliens?" scene.
I hope to see more of your work in the future!