1 - Carefully
2 - Clint Eastwood
3 - 2:30
4 - A femur
5 - Click the leftmost skip
6 - What (in the question number)
7 - Illegal
8 - H (on the keyboard)
9 - Blnd Pg
10 - 7 or 8 (count carefully)
11 - 4
12 - Click the dots in ascending order
13 - Corn flakes
14 - Quickly click the one it tells you to (dolphin and pigeon are on the left and the fork is on the right)
15 - >:C
16 - Click "Question" in the question
17 - C (on the keyboard)
18 - The dictionary
19 - A tin
20 - Lick (mash the mouse on Chris)
21 - Click and drag the . in the question number in between the 2 and the 1 and click the 2.1
22 - A yoglett
23 - Click exactly the amount of bubbles it tells you to then click the arrow
24 - Fart (click the word far in the question)
25 - Seaweed
26 - Yes
27 - Wow. The Impossible Quiz has sure gone downhill!
28 - The liver. (Drag Franks skin away from him and click the red bulge)
29 - A yoglett
30 - March (press left and right on the keyboard, left, right, left, right)
31 - NO U
32 - M (on the keyboard)
33 - You wrote it with your left hand!
34 - Biased
35 - P (on the keyboard)
36 - Move "bowel" in the question out of the way and click "Answer"
37 - Mash the mouse on the red button
38 - 25.81
39 - People die
40 - In my gentlemans area (or otherwise)
41 - Wipe their arse
42 - Same as question 30, (press left, right, left, right on the keyboard, but you'll have to do it MUCH faster)
43 - Type the word "cast"
44 - Drag the word "mouse" on to the word "here" then click the arrow
45 - Drag the word "ground" out of the way and fix those three pipes by clicking on the leaks
46 - This confuses me - sorry
47 - Move your mouse up and down the rod
48 - 1
49 - Click on Mars' many holes and spot until a phlovomite appears
50 - Click the hook until Chris destroys it.