I agree with the post below. My Vampire is level 37, 294 Vitality ( Over 30,000 HP), 562 Intelligence, I heal about 100,000 HP per SECOND and my mana regenerates from 0 to 400 in 1 critical hit. My character is quite literally invincible and yet I randomly get poisoned at RANDOM times and suddenly lose 90% of my HP per second and so the only way for me to survive it is to megakill like 50 enemies at a time.. once I run out of enemies to heal off of, if the poison remains I'm dead. I call is the CALAMITY because it is quite such. #WtfGlitch (I still rated 5* because up until nightmare mode and the calamity glitch, the game is great.)