Good Smoke
While the humor was bland, and the acting was below average, and the editing was near non existent (I heard the camera person actually laugh during a scene).
I'm not sure I understand the physics of the lasers. They appear and cause smoke when they hit things unless it's at the beginning where the guns simply make noise and nothing more?
the smoke effect was decent though, but it really seems like a showcase for mediocre special effects to be tossed into a film that has such a slow pace that even a turtle in a tar pit could keep up. That is, if there was any direction. Now it's no Ren and Stimpy of randomness, but a pee scene? Random useless poorly delivered and overused "I'm not dead yet" joke? Unexplained indistinguishable laser firing devices that fly away?
To help you out, because you obviously put SOME effort into this, write a script, stick to that script, practice the acting, don't fear taking more than one take, and when the whole thing is done, don't publish it, review it, check for errors with a critical eye, go back and fix those errors. THEN and ONLY then publish it.
Also, while it is my own personal opinion, this really doesn't belong on Newgrounds. There's not really any animated content. I've seen way more talented things get criticized for an overuse of simple tween animations and non animated video content.
You did do well with plagiarized sound effects and music though, it kind of helped to create a mood. Also fairly decent menu, and again, pretty decent smoke effect. Sadly, that's only 4 positives tossed in a giant heap of negatives.