In concept, it's definitely interesting, and a fitting sequel to the original Karoshi. Levels are still creative and unique (though some are more gags than puzzles)... the biggest difference is the physics. The game is noticably less smooth and responsive than the first game was. I assume a different engine was used. Karoshi slides around a lot more, jumps are occasionally delayed, and occasionally he would be forced to continue moving left or right after the arrow key was released--during general gameplay, not just in the levels where that was the gimmick.
It's still a fun game to play, and I recommend it to fans of the original. The gameplay just suffered a bit. On the bright side, this version has a quality setting (which the first did not), so that's deserving of some bonus points. Overall, I'll give it 4 points. A great game and a great sequel--it's just not quite as great as it could have been.
I notice the gun is gone in this version. I can't help but wonder if that's due to the questionable logic of him having one in the first game (but never using it) when the goal was to kill yourself. =P