This is some serious shit, man! I loved the crazy last part, it is totally my type of humour.
I can only suggest downloading profecional audio recording software (cool-edit, cubase or anything of the sort) and make some audio-tracks first, then just animate over the tracks. This greatly improves comedic timing and helps the voice-acting off its "fresh off the mic" feel. You also have more power over the sound-effects and background music.
Other than that, this is perfect. I hope this series lives long and kicks newgrounds ass.