An exception
I usually blam soundboards (oops, I think they might have been yours...), since I am not a big fan, and they're done on really bad quotes with bad sound. This one is an exception. The Simpsons has great little sounds (especially made by Homer). If you get a good collection started, it'll be awesome on future ones.
My only advice that I have to offer is to have most, if not all of your sounds be loud and high-quality. Most of them already are, but some were too quiet/had background noise. Like you've said, it takes a lot of work, but you can make this soundboard great by making the sounds all equal. Good work!