Some have written about the "Samson Option" as a retaliation strategy. In 2002, the Los Angeles Times published an opinion piece by Louisiana State University professor David Perlmutter which the American Jewish author Ron Rosenbaum writes "goes so far as to justify" a Samson Option approach:
"Israel has been building nuclear weapons for 30 years. The Jews understand what passive and powerless acceptance of doom has meant for them in the past, and they have ensured against it. Masada was not an example to follow—it hurt the Romans not a whit, but Samson in Gaza? What would serve the Jew-hating world better in repayment for thousands of years of massacres but a Nuclear Winter. Or invite all those tut-tutting European statesmen and peace activists to join us in the ovens? For the first time in history, a people facing extermination while the world either cackles or looks away—unlike the Armenians, Tibetans, World War II European Jews or Rwandans—have the power to destroy the world. The ultimate justice?"
Rosenbaum writes in his 2012 book How the End Begins: The Road to a Nuclear World War III that, in his opinion, in the "aftermath of a second Holocaust", Israel could "bring down the pillars of the world (attack Moscow and European capitals for instance)" as well as the "holy places of Islam." He writes that "abandonment of proportionality is the essence" of the Samson Option.
In 2003, a military historian, Martin van Creveld, thought that the Al-Aqsa Intifada then in progress threatened Israel's existence. Van Creveld was quoted in David Hirst's The Gun and the Olive Branch (2003) as saying:
"We possess several hundred atomic warheads and rockets and can launch them at targets in all directions, perhaps even at Rome. Most European capitals are targets for our air force. Let me quote General Moshe Dayan: 'Israel must be like a mad dog, too dangerous to bother.' I consider it all hopeless at this point. We shall have to try to prevent things from coming to that, if at all possible. Our armed forces, however, are not the thirtieth strongest in the world, but rather the second or third. We have the capability to take the world down with us. And I can assure you that that will happen before Israel goes under."
In 2012, in response to Günter Grass's poem "Was gesagt werden muss" ("What Must Be Said") which criticized Israel's nuclear weapons program, Israeli poet and Holocaust survivor Itamar Yaoz-Kest published a poem entitled "The Right to Exist: a Poem-Letter to the German Author" which addresses Grass by name. It contains the line: "If you force us yet again to descend from the face of the Earth to the depths of the Earth — let the Earth roll toward the Nothingness." Jerusalem Post journalist Gil Ronen saw this poem as referring to the Samson Option, which he described as the strategy of using Israel's nuclear weapons, "taking out Israel's enemies with it, possibly causing irreparable damage to the entire world."