I don't see anything to stop you from buying out a family in one day... Other families could maybe react to this, feel threatened? They don't. Player just repeatively hoardes money, starting with bribing press over 50%, and consequently bribing all city to 100% respect, safely upgrading areas and alcohol.
Other families don't seem to do anything remarkable at this point.
The fact that whole city shares your reputation is kinda unrealistic, I expected that when I buy out or shoot out a family, people of their former terrain will be suspicious.
The fact that the liquor doesn't firstly go to the most dry district is also not cool. They should be distributed that the engine tries to leave every district with same stock, so starting with the lowest numbers.
Would make to decent multiplayer.