The audio on this is pretty funny. The visuals are pretty good, but they could use a little bit of work.
There are times in this when you use a vibrating effect. It looks like you're cycling through two frames very quickly. What I'd recommend is adding a third frame and slowing it down by adding another frame into each picture. This will make things look less violent and strange.
Honestly, most of the rest of my advice is to move on from the mouse and practice with the tablet a bit more. Your characters could be a bit cleaner, but I'm going to blame that on the mouse and hope that you can produce something a bit cleaner with the bamboo. You might want to experiment with a thinner line, or even using the pencil tool. Either would help make the drawings look a little better.
Your extremes are well done though, and while I'd complain that the cartoon is a little short and the ending is pretty random, I will say that it didn't overstay it's welcome. Rather it was short and sweet and pretty funny.
Good luck, and I look forward to seeing what you produce in the future.