My favorite is Cinema 4D (obvious due to my username). It's kind of similar to Maya in layout, but it just feels better in my opinion. I can't really explain it, it's just personal preference.
Personally, I don't really like Blender. Don't get me wrong, the fact that it's free makes it automatically worth getting especially for all the stuff that it can do. I just never liked the layout. It always seemed like the developers purposely made everything so darn hard to find. The first time I used Blender, it took me 10 whole minutes to finally figure out how to pop in a freakin' cube. To me, that's just inexcusable.
But I do have a few friends who use Blender and they enjoy it. In the end, it's all personal preference. Each 3D software can do just about anything, it's just which you personally prefer for some bizarre reason or the other.