A bit too disruptive!
I have to agree with with the other two comments, the synth at :48 is WAY too loud. There's even that little retro-sounding part in the background during it and I can barely hear it, let alone the normal background. And this is just my personal taste, but I wonder if that synth could be replaced with an organ-like sound of some sort, I'm not sure why but I just get the urge to put it in there.
Speaking of those retro-style noises, I thought they sounded a bit out of place with the piano and the whole thing about most of the song having very subtle noises and then having these extremely flat synthetic noises jumping out. Couple that with the screaming loud melody and it's really quite disrupting. Although, I suppose, it works with the name of the song.
An interesting thing to note is that I think the ending of the song loops into the beginning almost seamlessly. If you haven't listened to it yet that way, try it out, it's really quite nice.