Wow, I am quite impressed by this. By the description, I thought you were saying at first that both Death and Bitterness were in this picture. Since there was no one with a scythe, I guess I was wrong. It seems like this is an image a lot of people can associate with. We have all had our days where everything just seemed to go wrong. Or maybe it was a metaphor for how smoking kills people?
The shading is wonderful in this as well. You get the sense that you're up close and in the action. Bitterness' skull seems to have a red tint to it. In fact, I seem to notice that a lot in drawings like this. Neither of the people look all that bitter. I guess that's hopeful.