So the whole point of this video was to beat the crap out of the dog, right? Because honestly, that's all I saw. The story is there only for to keep some cohesiveness for the whole animation, but in general it seems everything about this animation had one intent: Torture the crap out of the Duck Hunt dog. There were several parts that made no sense, that offered nothing to a narrative, that all seemed intent to bring severe harm to this dog (Like getting the needle up his nose and getting that virus)
I mean, it was good animation. A lot of quality sprite work, but I don't see the reason for a lot of the scenes. Some stuff gets dragged out for waaaay too long, the video is constantly being distracted by unimportant characters, and the overall punishment being given to the dog is probably excessive.
In short, it was good, but it could've been a lot better. For something you spent so much work on, I'm surprised you didn't put more into the story itself.