Surprisingly good, and with potential!
All of the humor in this is good, it shows creativitiy. This is practically a sitcom waiting to happen. You ever consider writing scripts for them? Seriously, we need some new ideas these days -- all these 'Friends' spoofs are freaking killing television.
Other than that, the art style was very good, if a little plain, and I loved the very last scene that spoofed the Street Fighter Game Over screen. A very good idea that shows even more of that sitcom potential. Only real drawbacks is that since the humor is similar to sitcoms, it seems a little too human for the actual plot -- come on, they're God's rejects, there should be a little more inhuman humor past the beginning scenes. That, and the huge filesize is really pushing it -- dial-up users may as well skip this one.
Regardless, let's see the second episode already.