Spooky, served it's purpose.
Harlequin type ichthyosis is some creepy look'n shit. Seriously.
It is hereditary, not induced by taking drugs while pregnant but what the hell, it really doesn't matter, big whoopty shit. Medical accuracy is not important here.
What IS important right now is the quality of this film.
It's tripy-scary like I imagin a bad acid trip would be, for animation it is difficult for me to rate because with the style that you were using suggests that you intended it to be surreal and it was. You could still guess what
The music was also creepy, which also seemed to be right in what you wanted.
Overall, you did what you seemed to have wanted to do and did it well. Good job, and I suggest watching this right before you go to sleep if you are prone to having nightmares.
Also, I highly urge people not to google harlequin type ichthyosis if they are faint of heart.