I kind of disagree with what you're saying. I'm fairly certain they weren't supposed to represent the seven deadly sins. Then again, those have really been applied to everyone. They were intentional with "Gilligan's Island" and "SpongeBob Squarepants". I think Two-Face probably has the best drawing. I know these characters fairly well.
I've never thought of Mr. Freeze as being destructive. I guess Lust would be perfect for Poison Ivy. She is probably the most well known femme fatale out there. I think Envy would be someone who became evil because of it. I don't think that's the Riddler's backstory.