The Hound possesses a superhuman healing factor derived from that of the mutant Wolverine that allows him to regenerate damaged or destroyed areas of his cellular structure at a rate far greater than that of an ordinary human. As such, he can regrow severed limbs or vital organs. The speed at which this healing factor works varies in direct proportion to the severity of the damage Deadpool suffers. This healing factor also affords Deadpool a virtual immunity to poisons and most drugs, as well as an enhanced resistance to diseases and an extended life span