Excellent game! One of the best I've seen in Flash, and I've played hundreds.
I have a few serious complaints, though:
First, for some reason, I keep dying at a specific point (seems to be 23-10-2050). The ending message says it was due to starvation, but there was NO indicator in the reports beforehand that anything was wrong with the base, and it happens even if I have 90+ days of water, 40+ days of oxygen, 20+ days of fuel, and all base systems online. If I load the autosave for that day, clicking on 'reports' sends me straight to the ending message. I verified that the catastrophe happened on a single day with no warning, by going to the nearby asteroid cluster (which I can reach in 1 day) repeatedly and checking the reports every day.
Second, at one point I was attacked by pirates who stole every single piece of cargo and money, and the following day, it said that I had negative oxygen, water and fuel. Obviously there was no way to recover and I had to reload, but it seems kind of silly to have negative of anything.
I've give 4.5 if the glitches were fixed, and possibly 5 if the UI elements were improved (I'm mostly thinking of combat hitboxes and the market interface; a 'sell all' button for each commodity would be nice).