One major glitch
When you die on the second part, your health is literally nothing. This means you can take as many hits as you want as long as you don't get a health powerup (which then makes you vulnerable again). Now I don't really have a problem with this except that if you do it, you can't complete the game. You just keep on going into that same last door to be sent to the retry/menu screen. You also have infinite adrenaline after part 2 starts, which again is anything but a disadvantage and could be written-off as a reward rather than a glitch.
I can tell you worked hard on this game, but its still a bit glitchy and the dificulty level spikes after the second part. The fact that you kept having to increase your adrenaline just to wall jump (among other things that are impossible to do without adrenaline in the game) was also a huge annoyance.