That's an interesting game, but I'd like to nitpick a few things...
In this game there are two very high-impact themes, as far as I can get it: sexual identity and suicide. They're both very strong topic, and I don't think it's easy to make them coexist in a single creation; this game doesn't end up feeling soppy, but it would have been better to concentrate on a single theme - the ending, for instance, would have been more effective without the very last part, with her - or him - near the roof edge; it creates an excessive pathos "load".
Secondly, I think the pixelated design of characters doesn't fit with the rich texture of the ambient - I'm not saying it's bad or ugly, but a more refined or flat design for the characters would have given a better overall visual coherence.
Finally, the recollection of piece to save the moon astronauts, the tree, too much stuff all relatively related to the two main topic. Again, I'm not saying it doesn't make sense, but the overall feeling gets a little dissipated in too many streams.
That's my opinion, and of course it's not the ultimate truth :) I just hope I'm giving you some interesting cue to work on.
Keep up the good work.