Ok, here's a quick walkthrough.
You won't be able to grab or interact with an item until you interact with something that provides a reason for it. That's what trips most people up. Also, you need to be on the hand icon.
First, walk around the first scene clicking on everything you can.
Go to second street at the right.
Grab garbage can lid, poster and click on the boxes.
Click on scaffolding overhead to get hammer.
Use hammer on boxes to get a bag of flour and a piece of wood.
Combine flour and garbage can lid.
Go back to first street and poke the overhead pipe with wood and QUICKLY go to second street and use lid with flour with the pipe with water flowing out before it stops flowing to create glue mix.
Combine glue with wood and glue covered wood with poster and stick it over the vent.
Door next to vent will open. Go in after talking to guard.
Read instructions on poster on wall, poke security camera with wood. Collect, battery, lens, and spanner. Go out, use spanner on pipe next to door. Go to second street, Talk to azurian.
go back to first street. Talk to guard. Go into room. Grab comic. Talk to guard. Go back into room and grab pencil. Use pencil on comic. Sell comic to guard. Go buy part from azurian. Build weapon. Use weapon on guard. go into big metal door.
Click on capacitor slot. Go back out and get glove off guard. Pull capacitors and stick them back in a different order so that the dials go red.