VY Canis Majoris is incredibly large compared to our planet but it is still a small speck on an amoeba when compared to the observable universe as a whole, which is roughly 93 billion light years in diameter (in other words, it would take light 93 billion years to go from one end to the other, and the Universe is only 13.2 billion years old)
And the observable universe itself is probably extremely small compared to the rest. I think I read somewhere that some scientists believe that the entire universe is so large, that if the Observable Universe was the size of a quarter, the entire universe would be the size of the planet Earth. Since your average quarter is about 1 inch in diameter and the Earth is roughly 8,000 miles in diameter, or approximately 506,880,000 inches, meaning that the entire universe would be 506,880,000 times larger than the observable universe of 93 billion miles, meaning the universe would be 47,139,840,000,000,000,000 light years in diameter.