Real shrill and harsh at points.
That can't be helped much for 8-bit music though, I know. You are great at writing melodies, which seems real rare on Newgrounds, but I'd like to hear some of the melodies developed more before you move on. The constant moving from melody to melody keeps the song from really going anywhere, I feel. Save the extra melodies that are worth saving for other songs and concentrate on three or four. One of the early melodies was brought back at the end, but it really shifted around too much, in my opinion.