The high saturation in this picture is really interesting, particularly in the reds and yellows. I like the contrast with bright figure vs. dark room, but I definitely think it would have been a bit cooler to expand more on the shadows to bring out the contrast. Overall the shapes are nicely surrealistic, which fits the color scheme and makes for a cartoony yet sober look and overall mood. The splotches do an exceptionally good job of mixing simple outlines with more complex particle textures.
I guess the only thing that really sticks out here is the symmetry of the nurse, which is somewhat strange considering that all monsters in Silent Hill bolster their eeriness by moving in a very unnatural and unsymmetrical fashion. Other than that you're in good shape.