Nintendo already tried it, and it got decent to mixed reviews.
See "Super Princess Peach"
Later on some time down the line it got criticism because "Women aren't always about being overly emotional." Ala peach's power cube.
Nintendo threw it in the gaming vault, never to see the light of day again, and now likes to pretend it doesn't exist.
Great art though, love me some Daisy as the assertive self-styled leader.