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Jan 25, 2009 | 2:59 PM EST

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There's only one proper way to learn science: through SONG!
This is a bio project about glycolysis, the first step in cellular respiration in all cells. It is the epic tale of a glucose molecule becoming two pyruvate. If you had trouble learning the steps before, rejoice-- nothing stays in your head like a catchy tune and a lack of vocal talent.
Credit also goes of course to my group members!

LYRICS*
A glucose molecule was floatin' around
the cytoplasm with other compounds
when suddenly 2ATP burst from the shade
and destabliz'd the bonds 'twixt atoms made
Glucose, unstable, began glycolysis :
'glucose' means sugar; splitting 'lysis'
for we split glucose to make energy
that we store in the bonds of ATP

from which we steal with phosphorylase
to turn glucose into glucose-6-phosphate
but this also turns ATP into ADP
a reaction which takes energy
then an isomerase enzyme makes isomers
rearranges G-6-P into something similar:
a fructose-6-phosphate molecule
different arrangement with the same formule (-a)

This is the Ultimate breakdown, of glucose for energy
compounds, enzymes, and conversions, too small for the eye to see
one compound will remain, I wonder what it will be
this is the Ultimate breakdown, of glucose for energy.

Phosphorylase took a bite out of ATP
like Bryn took a bite out of his sushi
with a phosphate subtrate + fructose-6-phosphate
to make fructose-1,6-biphosphate
this compound decomposed because t'was unsteady
it split into two: G-3-P and NADP
but isomerase changed di-hydroxy-acetone-phosph ate
which resulted int 2 glyceraldehyde-3-phosphat e

Then NAD took hydrogen with hydrogenase
it became NADH+H while phosphorylase
took a phosphate group from the ATP compound
making 1,3-biphosphoglycerate with new phosphate bound
which was made very pointless when in the next step
ADP reclaimed the phosphate group
with phosphorylase, and ATP was made,
along with a molecule of 3-phosphorylate.

This is the Ultimate breakdown, of glucose for energy
compounds, enzymes, and conversions, too small for the eye to see
one compound will remain, I wonder what it will be
this is the Ultimate breakdown, of glucose for energy.

Compounds were changed in quick succession
in glycolysis of cellular respiration
which takes a glucose molecule and breaks it apart
-- glycolysis is only the start.
of this long process which all cells complete
even bacteria and the plants that we eat.
it creates the necessary energy
to carry out the cell's activities

A Glucose destabliz'ed by 2ATP and
becomes glucose-6-phosphate with one P
fructose-6-phosphate, fructose-1,6-phosphate
and two glyceraldehyde-3-phosphat e,
1,3-biphosphoglycerate, 3-phosphoglycerate,
which is rearranged into 2-phosphoglycerate
which is dehydrated by dehydrase
to make phosphenol pyruvate
they all came from each other lightning fast
to release the energy in glucose stashed
its a process that happens constantly
unless it runs out of NAD+

and glycolysis raged in entities
many enzymes were used but eventually
the product to which this process equates:
2 molecules of pyruvate!

This is the Ultimate breakdown, of glucose for energy
compounds, enzymes, and conversions, too small for the eye to see
one compound will remain, I wonder what it will be
this is the Ultimate breakdown...
this is the Ultimate breakdown...
this is the Ultimate breakdown...
of glucose for energy.

*the tune belongs to lemondemon

Reviews


sammontaguesammontague

Rated 5 / 5 stars January 25, 2009

brilliant

loved it



devilskill66devilskill66

Rated 4.5 / 5 stars January 25, 2009

lol creative

lol similar to the ultimate showdown, educational though, its pretty good. I only issue is the subtitle lyrics are slower than your singing, but thats just a minor techniality. gj.



Rafeki97Rafeki97

Rated 4 / 5 stars January 25, 2009

words

only bad thing is that you need to get the words to match up with the video



WuigiStarWuigiStar

Rated 4 / 5 stars January 25, 2009

...

Great idea, crappy syncing, and the newgrounds play button just stays through the whole movie ;/
Lyrics are one line behind the song



simbriansimbrian

Rated 3.5 / 5 stars January 25, 2009

a good try

I love the idea behind this, which is why you get a decent score.

The main problem here was the lyrics. You were trying to say too many words in too short a time so I could only really understand it by reading the subtitles. I'm also pretty sure I heard people laughing while you were recording it.

Still cool though. I'm sure you'll do well on this assignment.