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Oh, and I forgot the Dragon Tank from Chrono Trigger. Awesome.

METAL SLUG
It has tons of epic bosses.

#1 caim vs his own dragon in chaos mode DRAKENGARD1

#2 darius ship vs titanium aloy(or lantern somthin crazy like that) DARIUS TWIN

#3 tidus and team vs jet/sin FFX

#4 kirby vs metaknight KIRBY NIGHTMARE IN DREAM LAND

#5 predator vs flying alien ALIEN VS PREDATOR SNES VERSION

#6 predator vs snake alien ALIEN VS PREDATOR SNES VERSION

#7 contra guy vs begining foe in i think 4th level (the giant rocket water sking robot that you kill wiel you ride a missile CONTRA SHATTERED SOLDIER (INCREDABLY HARD TILL YOU GIT IN TO IT!!! I USED 99LIVES CODE AND WITH 2 PEOPLE DIED ON THIS LEVEL PLAYED ALONE NO CODES A FEW YEARS LATER AND BEAT THE GAME!!!!!!)

#8 fly swatter vs mech fly MARIO PAINT (NOT JOKING)

#9 guitar hero battle with loe GUITAR HERO 3

#10 worms charecter vs boggy pete sheep ice mission WORMS 3D

THIS IS A PICTURE OF CONTRA THING...NOT GOOD SHOT

ANY ONE PLAY SHATTERD SOLDIER???

**SPOILER FOR MGS4**

Fighting Liquid at the end of the game was so fucking EPIC, my cat shrieked and ran away as he appeared. The controls were easy to use, and I LOVED the fact that the music shifts throughout the series during different stages of the fight, it was very nostalgic, and ending with the MGS4 Old Snake theme, damn that was awesome.

the battle between a yes/no to play from your mom and dad! XD!

Maybe not epic-epic, but I thought the final battle in Gears of War was pretty freaky.

Epic would be the battle against that huge crawly guy from GoW though (I'm forgetting the name, but the guy that dies from falling into the lava then bursts out and shit).

Oops, spoiler.

Sonic and Shadow vs. the Biolizard in Sonic Adventure 2

Mine as well would be Link vs Ganon from LoZ:OoT

Hm lemme see...

Justin versus Baal (final form)-Grandia
Justin versus Gaia-Grandia
Ryudo versus Melfice-Grandia 2
Orphan versus Gaia-Orphan Scion of sorcery
Vyse and crew versus the Giga's-Skies of Arcadia
Dark Demon-Dynamite Headdy
Doomsday Robotnik-S3&K
Adolf Hitler-Wolfenstein 3D
Ganondorf-OOT, WW.
Majora's Mask-MM (Easy, but had a sense of, "Come on you mother fucking piece of shit! You've driven me insane always going back in time and collecting those fucking mask's, and i'm gonna smash my sword into your fucking cranium!").
Gary/Blue-Pokemon Yellow (Back when I was a lad playing Yellow, beating Blue was a big fucking deal!)
Death Bringer-Golden Axe (Badass battle)
The bitches from Streets of rage... You know who I mean, the fucking annoying one's, beating them is epic!-Streets of rage

That's it for now.

I don't understand why people are mentioning Psycho Mantis. I thought it was innovative, but not epic.

The Boss vs Naked Snake.

1. Big Boss vs The Boss (MGS3)
2. Kratos vs Zeus (GoW II)
3. Link vs Dragon (LoZ:TP)