Audio Apps:
Acid Pro 5 - I've been using Acid forever and a day - I love it
Reaktor 5 - Indescribably delicious audio app - defies description - does everything
SoundForge 8 - been using SoundForge forever too - great program
Audition 1.5 - Very nice as a rewire host and great as a general sound app but I'm much more comfortable using SoundForge for editing and processing
CMStudio - a very decent piece of freeware
Reason 3 - My most recent purchase - very nice so far but I've only logged about 4 hours on it so far - so I'm still quite new at it.
an assortment of VSTi's - this, that and the other - which are pretty much all obsolete because of Reaktor 5 - but they're still fun here and there.
On occasion I use a bunch of other 'smaller' programs - scratch, granulizer, Moonfish, Tu2, Magix - those sorts of things - mostly for very specific purposes...
I use an Edirol PCR-30 for my input
This isn't all inclusive but I think I've covered the main stuff... and there you have it...