I fly pretty much every 4-5 weeks since...I was a child up to now.
I suggest, getting insanely drunk. Just drink a bit before take off and get trashed on the plane.
I do this because I don't like flying, plus everything becomes more entertaining although it did make me end up crying at cartoons on the plane but yeah, nothing to it really, its an unusual feeling.
The plane tends to make a lot of noises ( flaps/gears/fuel dump..etc ) so don't get worried.
Drink plenty of fluids on top of that alcohol, get up and walk around every now and then. Enjoy the flight!