Nathan Drake (Uncharted): Now, don't get me wrong. I don't dislike him. It's just that he sometimes talks to himself too much and cracks too many jokes, especially in situations that would personally make me forget about any sense of humor. Other than that, he's lovable.
Chloe Frazer (Uncharted): While she does seem to become more of a considerate person towards the end of the second game, she is mostly unreliable and unpredictable.
Hugo (Street Fighter X Tekken): In fighting games, I've always been one to prefer small and fast characters (ironically, his partner Poison is one of my favorites for this reason). Hugo is probably the slowest character in the entire roster. His looks or personality don't intrigue me either. He's a very shallow weird man with weird hair and weird clothes.
Kano (Mortal Kombat): He just doesn't fit my play style somehow, and he always seems to be the same guy: a vicious criminal who hates cops.
Hershell Biggs (L.A. Noire): He's an immensely unfriendly bastard until the end. I was hoping to see some character development in him but not much has happened except that he developed a reluctant respect for Cole, but even that is debatable.
Stanley Poole (Bioshock): Ugly, sinister fellow.
Sofia Lamb (Bioshock): While she does have an outstanding voice, I just failed to respect her as much as I respected Andrew Ryan. Not to mention, she keeps repeating the phrase "Ask yourself."
Paco Mendes (Heavy Rain): Never seen a guy as obnoxious as this one. Definitely deserved that lamp in the head.
Frank West (Dead Rising): The problem with this guy is that although he has shown considerable character development between Dead Rising and Dead Rising: Off the Record, both of his personalities are pretty obnoxious to me. Let me elaborate. In the former game, he is a determined but somewhat cowardly and awkward guy. He just lacked charisma somehow. In the latter game, not only is he very confident, he has also become a bit of a bastard. He gives Stacy a pretty hard time about his suspicions on her, he can perfectly talk back to psychopaths, he's just ruder in general.
Rebecca Chang (Dead Rising): Being amongst zombies must have made her desperate for men, for the whole thing she does in the entire game is to flirt with the protagonist, get in trouble, get saved by the protagonist, and resume flirting.
Francis (Left 4 Dead): Back when I was a L4D freak, I played as almost all characters except for Francis. He's a cocky scumbag who never really gets along with anyone in the group. And despite his tough guy attitude, he screams like a girl when knocked down.
Hwoarang (Tekken): He has awesome kicks, yes. But he's extremely arrogant.