Who would like to see an MLP anime franchise be made? The anime could be done by the same people who did the animation for Sonic X (though have different writers). In it there would be many new characters, and we'd see more creatures and races, as well as new locations in Equestria and places outside of it. It can come in different formats: The TV series, movies, OVAs, specials, and a spinoff series called "Equestria Chronicles".
The TV series would be the anime franchise's nerve center. It would do things that FiM can't, like having more dramatic, intense, and adventure oriented moments, but still have good humor and slice of life stuff. There would also be a bit more romance involved with the mane 6, as there would be more major stallion characters other than Big Mac and Shining Armor. Some antagonists like Trixie and Flim Flam brothers would be recurring characters. There would also be new villains, and Chrysalis would also return.
The film series would have a movie coming out each year, and they would have more elaborate animation and a large scale plot. They could have their own villain(s) and they would have their share of action-y, dark and emotional moments, but still have humor in them.
The OVAs would be told just like the MLP comics; each OVA being like a comic arc. Say if there is a comic arc that has four issues, each part of an OVA would be as long as the two issues of that arc. The OVAs themselves would have their own individual plots. While their animation quality would be as up to par as the movies, it would still be better than the TV series.
The specials would basically be made for TV movies, with stories involving the mane 6. They'd be random stories involving the main characters, mostly slice of life.
Equestria Chronicles would be another TV series that would have hour long episodes that would have individual stories taking place in Equestria's timeline. If anyone has watched the video series "Historical Equestria", episodes would be about that stuff. Each season would have six episodes.