My reaction? Simple: Don't get caught. If you seriously need to do it, don't leave a trail. Think how the police, the Feds, and anyone else involved would think, and know what they're looking for. Don't give it to them.
This is hypothetical, I take it? I mean, obviously, it's wrong to murder anyone (no matter if you're religious or atheist). I don't condone, nor do I encourage anyone to think about murdering anyone. But, of course, I see nothing wrong with speaking about anything in the hypothetical context.