This is just personal curiosity.
Newgrounds is an awesome site, but we all come here for different reasons and because of that I'm sure we all have different things we'd like to see happen. I'm curious as to what you like to see Newgrounds as in 5 10, or 15 years.
This isn't a feature request topic. If you ask for it, chances are, it'll only happen if it was going to happen anyway. I'm not staff, I'm a moderator who's just a user who can delete things. So, if you tell me you want flying hippos on the front page, I've got just as much power to make that happen as you do.
Anyways, my vision for what I'd like Newgrounds to become:
I'd love to see something that engineered to further develop communication & collaboration on all levels while giving individuals a little more control over how they present themselves. If you've ever been to source forge you'll have an idea of what I'm talking about, but that's only hinting at it.
I want to see an online publishing software website of sorts and I think Newgrounds is in the prime position to do it. You have a "Create Project" link in your user profile. It hooks you up with the ability to create forums, albums of art & music, scripts and the ability to upload a quantity of files. You have the capability to add users into your projects. You can put parts of your project into preview mode. And importantly, everything is versioned.
On the userpage, you'd have the capability to add more too it. I'm assuming the website is eventually going widescreen, and so there'd be a lot more room on your userpage. It'd be really cool if newgrounds opened up some space for developers to create "flash apps" which could interact or do something cool. They'd be like widgets you could put up on your site and there could even be a small portal for them. More importantly, you'd have the organizational capabilities you have in the projects here as well. You could create albums of any content on the site and write them up however you want.
If you like horror games, you're free to collect your favorites, review them and then people can play them right on your userpage. If you have a group of people that like that kind of stuff, they could team up as well.
In this vision, I've assumed the art portal obtained albums, that the audio portal became a little bit better, and that flash content was less about static pages and collections of those pages and became a bit more mobile and viral just in the site itself. Additionally, I'm assuming a writing portal exists in some format as well and that blogs are far more accessible and can host richer content or be grouped together as well.
As far as the front page. I wouln't change much. I'd make it go widescreen and then, I'd probably make the game & video sections verticle with art & writing just below them with hotlinks up above.
It might even be possible to embed a flash player on the front page which loads the selected movie so that you don't have to navigate away from the front page to view the submission. Something similar could happen with the portal where you have a listing of recent entries on the left and you view the actual movie on the right, vote & review and then just click the next movie you want. Sort of like the way frames used to work, but this would be more javascript intensive.
Finally, it would be awesome to see some wave integration. I think Wave is really going to be a huge deal and offers some really great features. Newgrounds might want to look into either emulating or setting up its own wave server for its developers.