Heh love the OP's great attempt at trying to look hardcore. Anyway the hardest narcotic I've done would have to be either Ecstasy or Mushrooms, which one is more harmful to the system is for you to decide. I stopped smoking weed after I realized it was making me incredibly paranoid, and in turn made me depressed when I somehow convinced myself that this paranoia would now last forever.
Ecstasy and Mushrooms (not combined, that would be suicide), are definitely some of THE greatest experiences I have ever... well... EXPERIENCED.
The first time I took E I was quite a noob. I popped 2 caps and ended up in the middle of a dance covered in sweat, 3 women, a hickey, and no shirt (I never did find my shirt). Now I know that may sound like many a Newgrounder's fantasy come true, but holy hell did I feel retarded for the next day after the stunts I pulled.
The next 2 times I took E were definitely more relaxed, and were just a good old pure euphoric high, and the experience was sublime. I highly recommend everyone give Ecstasy a go at least ONCE in their lives, if not to simply see how insanely happy your neurochemistry is capable of making you feel. After the first or second time however, stop, as continued use will eventually lead to permanant brain damage and back pains (TRUST ME ON THE BACK PAINS).
Mushrooms is a wholly more mystical experience altogether. Now I've only done Mushrooms once, and don't remember the exact weight of the dose I took (Somewhere between 1 - 2g), but holy hell does it take you on the introspective journey of a lifetime.
Basically my cousin who was leaving to Poland refused to risk taking it over the border, and instead left it in my possession, and gave me his blessing before leaving North America forever. Now having 1 day to clean the house before my parents came home from their vacation, I decided that if I consumed the shrooms now, it would make cleaning so much more enjoyable.
The idea was a complete failure. The broom ended up on the floor where I had left it before taking the shrooms, and instead I spent the day buying dozens of bags of skittles from the gas station, believing that the walls themselves were breathing with me, and laughing at the EXACT same episode of Futurama THREE times in a row before realizing I had already seen it.
The next day I looked in my sketchpad and found pictures of boob-pillows, and how to properly use them drawn all over the page, as well as a journal entry saying how I felt like both Ghandi and Jesus combined.
Anyway, that left me with pretty much 4 hours to clean the entire home, and a great journey to reflect on.
I will end this long-ass fucking story that most of you will no doubt scroll over without bothering to read, with a simple request: That all of you experiment with hallucinogens or narcotics at LEAST ONCE, as it can be quite a learning expeirence. Except Heroin, Crack, and Meth. I forbid you to do those. They'll give you bad teeth... and stuff...