I just thought of this one. We need a remake to Earthbound. That was one of my favorite RPGs from back in the day. It was a long game, it was somewhat difficult but not too difficult (except for the final boss who is INCREDIBLY EASY provided you know what to do), and there were lots of things to do in the game.
It also needs a sequel, and I don't count Mother 3 as a sequel. Mother 3 was a good game, but there was no coinciding story line with Mother 2 (Earthbound).