The legendary Amen loop has been around since samplers were invented (if you don't know what I'm talking about, watch this video) and it's amazing to see what good DJs can do with it! I've picked up a CD from Russian DnB artist "Technical Itch", and he uses nothing but the Amen for the whole thing. He sliced it up and ran it though some very effective effects, and the result is very inspiring.
I'm sure many other DJs do that too, but at the moment, he's at the top of my creativity list. What's the best use of the Amen that you've ever heard?