The only issue I have with our tech getting smaller and smaller, is not only will we eventually get down to insectums of light we are already having issues with Quantum tunneling.
For those who don't know what that is, think of it this way.
You have a wall, and you're throwing tennis balls at it. Eventually one of those balls will hit the wall, disappear, reappear on the other side and keep moving with the inertia it hit the wall with. That is our current issue we need to overcome.