This single image took me about 2 months (including the planning phase). It was modeled, textured, rendered using Modo 10.2. Plant models come from Plant Factory. Substance Designer was used for the majority of textures (a first in SideTrip).
The 2D style comes from using a program called Synthetik StudioArtist 5 which hosts a lot of unusual techniques to paint an image. While the majority of the program runs auto-paint, you can of course manually paint stuff while keeping some of the neat AI behaviors.
The rest of this image was produced using ClipStudio Paint and Photoshop.